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Dendritic cells activated by an anti-inflammatory agent induce CD4+ T helper type 2 responses without impairing CD8+ memory and effector cytotoxic T-lymphocyte responses

Wang, Yang; Da'Dara , Akram A; Thomas , Paul G; Harn , Donald A


Summary Prevalence of pro-inflammatory diseases is rising in developed country populations. The increase in these diseases has fuelled the search for new, immune suppressive, anti-inflammatory therapies, which do not impact, or minimally impact, CD4+ and/or CD8+ T-cell-mediated immunity. The goal of this study was to determine if antigen-presenting cells (APCs) activated by the anti-inflammatory oligosaccharide, lacto-N-fucopentaose III (LNFPIII), would have an impaired ability to drive CD4+ T...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Immunology
DOI: 10.1111/j.1365-2567.2009.03193.x


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