Dendritic cells activated by an anti-inflammatory agent induce CD4+ T helper type 2 responses without impairing CD8+ memory and effector cytotoxic T-lymphocyte responses
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Wang, Yang; Da'Dara , Akram A; Thomas , Paul G; Harn , Donald A
Description
Summary Prevalence of pro-inflammatory diseases is rising in developed country populations. The increase in these diseases has fuelled the search for new, immune suppressive, anti-inflammatory therapies, which do not impact, or minimally impact, CD4+ and/or CD8+ T-cell-mediated immunity. The goal of this study was to determine if antigen-presenting cells (APCs) activated by the anti-inflammatory oligosaccharide, lacto-N-fucopentaose III (LNFPIII), would have an impaired ability to drive CD4+ T...[Show more]
Collections | ANU Research Publications |
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Date published: | 2010 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/25028 |
Source: | Immunology |
DOI: | 10.1111/j.1365-2567.2009.03193.x |
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01_Wang_Dendritic_cells_activated_by_2010.pdf | 551.17 kB | Adobe PDF | Request a copy |
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