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Immunopathogenesis of poxvirus infections: forecasting the impending storm

Stanford, Marianne M.; McFadden, Grant; Karupiah, Gunasegaran; Chaudhri, Geeta

Description

Variola virus, the causative agent of smallpox, is a member of the poxvirus family and one of the most virulent human pathogens known. Although smallpox was eradicated almost 30 years ago, it is not understood why the mortality rates associated with the disease were high, why some patients recovered, and what constitutes an effective host response against infection. As variola virus infects only humans, our current understanding of poxvirus infections comes largely from historical clinical data...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/24993
Source: Immunology and Cell Biology
DOI: 10.1038/sj.icb.7100033

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