Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients
Objectives: We evaluated whether the measurement of serum phosphorylated neurofilament heavy chain (pNF-H) titre is likely to be a valid biomarker of axonal injury in multiple sclerosis (MS). Methods: Serum pNF-H concentrations were measured by ELISA in cases with relapsing-remitting (RR)-MS (n=81), secondary progressive (SP) MS (n=13) and primary progressive (PP)-MS; n=6) MS; first demyelinating event (FDE; n=82); and unaffected controls (n=135). A subset of MS cases (n=45) were re-sampled on...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Neurology, Neurosurgery & Psychiatry|
|01_Gresle_Serum_phosphorylated_2014.pdf||350.43 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.