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Membrane Potential Changes in Dendritic Spines during Action Potentials and Synaptic Input

Palmer, Lucy; Stuart, Gregory J


Excitatory input onto many neurons in the brain occurs onto specialized projections called dendritic spines. Despite their potential importance in neuronal function, direct experimental evidence on electrical signaling in dendritic spines is lacking as their small size makes them inaccessible to standard electrophysiological techniques. Here, we investigate electrical signaling in dendritic spines using voltage-sensitive dye imaging in cortical pyramidal neurons during backpropagating action...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Journal of Neuroscience
DOI: 10.1523/JNEUROSCI.5847-08.2009


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