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The influence of platelet membranes on tumour cell behaviour

Coupland, Lucy; Hindmarsh, Elizabeth; Gardiner, Elizabeth; Parish, Christopher


The significant role of platelets in the protection of tumour cells from immune attack and shear forces and the promotion of tumour cell extravasation from the bloodstream in the process of haematogenous metastasis have been extensively studied. The role of platelets, and in particular platelet membranes, in the promotion of a more metastatic phenotype in tumour cells is a more recent and, therefore, less well-recognised area of research. This review article summarises studies that have focused...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Cancer and Metastasis Reviews
DOI: 10.1007/s10555-017-9671-3


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