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The association of falling insulin requirements with maternal biomarkers and placental dysfunction: A prospective study of women with preexisting diabetes in pregnancy

Padmanabhan, Suja; Lee, Vincent W. S; Mclean, Marc; Athayde, Neil; Lanzarone, V; Khoshnow, Qemer; Peek, Michael; Cheung, N Wah

Description

OBJECTIVE To investigate the association of falling insulin requirements (FIR) among women with preexisting diabetes with adverse obstetric outcomes and maternal biomarkers longitudinally in pregnancy. RESEARCH DESIGN AND METHODS A multicenter prospective cohort study of 158 women (41 with type 1 diabetes and 117 with type 2 diabetes) was conducted. Women with FIR of ≥15% from the peak total daily dose after 20 weeks' gestation were considered case subjects (n = 32). The primary outcome was a...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/248715
Source: Diabetes Care
DOI: 10.2337/dc17-0391

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