Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA
-
Altmetric Citations
Kretzmann, Jessica A.; Ho, Diwei; Evans, Cameron; Plani-Lam, Janice Hiu Chor; Garcia-Bloj, Benjamin; Mohamed, Ahmed Elaaf; O'Mara, Megan; Ford, Ethan A.; Tan, Dennis E K; Lister, Ryan; Blancafort, Pilar; Norret, Marck; Iyer, Swaminathan
Description
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic intervention. Although efficiencies and specificities of genome editing technologies have improved with the development of TALEs and CRISPR platforms, intracellular delivery of these larger constructs still remains a challenge using existing delivery agents. Viral vectors, including lentiviruses and adeno-associated viruses, as well as some non-viral...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2017 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/248328 |
Source: | Chemical Science |
DOI: | 10.1039/c7sc00097a |
Access Rights: | Open Access |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Kretzmann_Synthetically_controlling_2017.pdf | 974.68 kB | Adobe PDF |
This item is licensed under a Creative Commons License
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator