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Population Genomic Analysis of a Pitviper Reveals Microevolutionary Forces Underlying Venom Chemistry

Aird, Steven D.; Arora, Jigyasa; Barua, Agneesh; Qiu, Lijun; Terada, Kouki; Mikheyev, Alexander

Description

Venoms are among the most biologically active secretions known, and are commonly believed to evolve under extreme positive selection. Many venom gene families, however, have undergone duplication, and are often deployed in doses vastly exceeding the LD50 for most prey species, which should reduce the strength of positive selection. Here, we contrast these selective regimes using snake venoms, which consist of rapidly evolving protein formulations. Though decades of extensive studies have found...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/247320
Source: Genome Biology and Evolution
DOI: 10.1093/gbe/evx199
Access Rights: Open Access

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