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A Bayesian evaluation of human mitochondrial substitution rates

Ho, Simon; Endicott, Phillip


Accurate estimates of mitochondrial substitution rates are central to molecular studies of human evolution, but meaningful comparisons of published studies are problematic because of the wide range of methodologies and data sets employed. These differences are nowhere more pronounced than among rates estimated from phylogenies, genealogies, and pedigrees. By using a data set comprising mitochondrial genomes from 177 humans, we estimate substitution rates for various data partitions by using...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: American Journal of Human Genetics
DOI: 10.1016/j.ajhg.2008.01.019


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