Multiple functional self-association interfaces in plant TIR domains
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Zhang, XiaoXiao; Bernoux, Maud; Bentham, Adam; Newman, Toby E.; Ve, Thomas; Casey, Lachlan W.; Raaymakers, Tom M.; Hu, Jian; Croll, Tristan I.; Schreiber, Karl; Staskawiczj, Brian J.; Williams, Simon
Description
Toll/interleukin-1 receptor/resistance protein (TIR) domains are present in plant and animal innate immunity receptors and appear to play a scaffold function in defense signaling. In both systems, self-association of TIR domains is crucial for their function. In plants, the TIR domain is associated with intracellular immunity receptors, known as nucleotide-binding oligomerization domain-like receptors (NLRs). Previous studies from several plant NLRs have identified two distinct interfaces that...[Show more]
Collections | ANU Research Publications |
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Date published: | 2017 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/243965 |
Source: | PNAS - Proceedings of the National Academy of Sciences of the United States of America |
DOI: | 10.1073/pnas.1621248114 |
Access Rights: | Open Access |
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File | Description | Size | Format | |
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ZhangPNASRevFinal.doc | Author Accepted Manuscript | 313.5 kB | Microsoft Word | |
MainFiguresRevFinal.pptx | Author Accepted Manuscript | 14.89 MB | Microsoft Powerpoint XML |
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