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Midsagittal corpus callosum area and conversion to multiple sclerosis after clinically isolated syndrome: A multicentre Australian cohort study

Odenthal, Cara; Simpson, Steve; Oughton, Justin; Van Der Mei, Ingrid; Rose, Stephen; Fripp, Jurgen; Lucas, Robyn; Taylor, Bruce; Dear, Keith; Ponsonby, Anne-Louise; Coulthard, Alan


INTRODUCTION: Patients presenting with clinically isolated syndrome (CIS) may proceed to clinically definite multiple sclerosis (CDMS). Midsagittal corpus callosum area (CCA) is a surrogate marker for callosal atrophy, and can be obtained from a standard MRI study. This study explores the relationship between CCA measured at CIS presentation (baseline) and at 5 years post presentation, with conversion from CIS to CDMS. The association between CCA and markers of disability progression is...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Journal of Medical Imaging and Radiation Oncology
DOI: 10.1111/1754-9485.12570


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