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Pulmonary Function, Cognitive Impairment and Brain Atrophy in a Middle Aged Community Sample

Sachdev, Perminder Singh; Parslow, Ruth; Wen, Wei; Maller, Jerome; Kumar, Rajeev; Christensen, Helen; Jorm, Anthony F; Anstey, Kaarin


Objective: To determine the relationship of lung function to brain anatomical parameters and cognitive function and to examine the mediating factors for any relationships. Methods: A random sub-sample of 469 persons (men = 252) aged 60-64 years from a larger community sample underwent brain magnetic resonance imaging scans and pulmonary function tests (forced vital capacity, FVC, forced expiratory volume in the first second, FEV1). Subjects were assessed for global cognitive function, episodic...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Dementia and Geriatric Cognitive Disorders
DOI: 10.1159/000091438


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