Using minimalist self-assembling peptides as hierarchical scaffolds to stabilise growth factors and promote stem cell integration in the injured brain
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Rodriguez, Alexandra; Bruggeman, Kiara; Wang, Yi; Wang, T. Y.; Williams, Richard James; Parish, Clare L.; Nisbet, David
Description
Neurotrophic growth factors are effective in slowing progressive degeneration and/or promoting neural repair through the support of residual host and/or transplanted neurons. However, limitations including short half‐life and enzyme susceptibility of growth factors highlight the need for alternative strategies to prolong localised delivery at a site of injury. Here, we establish the utility of minimalist N‐fluorenylmethyloxycarbonyl (Fmoc) self‐assembling peptides (SAPs) as growth factor...[Show more]
Collections | ANU Research Publications |
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Date published: | 2018-03-12 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/241070 |
Source: | Journal of tissue engineering and regenerative medicine |
DOI: | 10.1002/term.2582 |
Access Rights: | Open Access |
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File | Description | Size | Format | Image |
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term.2582.pdf | Author Accepted Manuscript | 878.93 kB | Adobe PDF |
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