Structure-activity delineation of quinones related to the biologically active Calothrixin B
Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.
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|Source:||Bioorganic and Medicinal Chemistry Letters|
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