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Structure-activity delineation of quinones related to the biologically active Calothrixin B

Bernardo, Paul; Chai, Christina; Le Guen, Maurice; Smith, Geoffrey D; Waring, Paul

Description

Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/23878
Source: Bioorganic and Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2006.09.090

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