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Identification of candidate genes for devil facial tumour disease tumourigenesis

Taylor, Robyn L.; Zhang, Yiri; SchÖning, Jennifer Petra; Deakin, Janine

Description

Devil facial tumour (DFT) disease, a transmissible cancer where the infectious agent is the tumour itself, has caused a dramatic decrease in Tasmanian devil numbers in the wild. The purpose of this study was to take a candidate gene/pathway approach to identify potentially perturbed genes or pathways in DFT. A fusion of chromosome 1 and X is posited as the initial event leading to the development of DFT, with the rearranged chromosome 1 material now stably maintained as the tumour spreads...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/238584
Source: Scientific Reports
DOI: 10.1038/s41598-017-08908-9
Access Rights: Open Access

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