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Fine-Scale Structure Analysis Shows Epidemic Patterns of Clonal Complex 95, a Cosmopolitan Escherichia coli Lineage Responsible for Extraintestinal Infection

Gordon, David; Geyik, Sarah; Clermont, Olivier; O'Brien, Claire; Huang, Shiwei; Abayasekara, Charmalie; Rajesh, Ashwin; Kennedy, Karina; Collignon, Peter; Pavli, Paul; Rodriguez, Christophe; Johnston, Brian D.; Johnson, James R; Decousser, Jean-Winoc; Denamur, Erick


The Escherichia coli lineage known as clonal complex 95 (CC95) is a cosmopolitan human-associated lineage responsible for a significant fraction of extraintestinal infections of humans. Whole-genome sequence data of 200 CC95 strains from various origins enabled determination of the CC95 pangenome. The pangenome analysis revealed that strains of the complex could be assigned to one of five subgroups that vary in their serotype, extraintestinal virulence, virulence gene content, and antibiotic...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: mSphere
DOI: 10.1128/mSphere.00168-17
Access Rights: Open Access


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