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Causes and mechanisms of adipocyte enlargement and adipose expansion

Haczeyni, Fahrettin; Bell-Anderson, Kim S.; Farrell, Geoffrey


Adipose tissue plays a significant role in whole body energy homeostasis. Obesity-associated diabetes, fatty liver and metabolic syndrome are closely linked to adipose stress and dysfunction. Genetic predisposition, overeating and physical inactivity influence the expansion of adipose tissues. Under conditions of constant energy surplus, adipocytes become hypertrophic and adipose tissues undergo hyperplasia so as to increase their lipid storage capacity, thereby keeping circulating blood...[Show more]

CollectionsANU Research Publications
Date published: 2017-12-15
Type: Journal article
Source: Obesity Reviews
DOI: 10.1111/obr.12646


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