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An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event

Tettey, Prudence; Simpson, Steve; Taylor, Bruce; Ponsonby, Anne-Louise; Lucas, Robyn; Dwyer, Terry; Kostner, Karam; Van Der Mei, Ingrid

Description

ABSTRACT Objective To investigate the prospective associations between adiposity and lipid-related variables and conversion to multiple sclerosis (MS), time to subsequent relapse and progression in disability. Methods A cohort of 279 participants with a first clinical diagnosis of central nervous system demyelination was prospectively followed to 5-year review. Height, weight, waist and hip circumference were measured, and serum samples taken for measurement of lipids and...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/232487
Source: Journal of Neurology Neurosurgery and Psychiatry
DOI: 10.1136/jnnp-2016-315037

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