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A dynamic mathematical model of red blood cell clinical demand to assess the impact of prolonged blood shortages and transfusion restriction policies

McQuilten, Zoe K; Mercer, Geoffry; Phillips, Louise; Luangwilai, Thiansiri; Brown, Richard; Ozolins, Ieva; Cheng, Allen; Wood, Erica


Background Estimating change in clinical demand for red blood cells (RBCs) from a disaster, as well as triaging introduced in response, is essential to plan effectively for a major blood shortage. We aimed to develop a RBC demand model to assess the impact of restriction policies on RBC use and patient outcomes.Study Design and Methods A compartmental dynamic model was developed in which patients require RBCs acutely (within 1 hr), urgently (24 hr), semiurgently (1-7 days), or nonurgently;...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Transfusion
DOI: 10.1111/trf.12525


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