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Specific control of cell-material interactions: Targeting cell receptors using ligand-functionalized polymer substrates

Rodda, AE; Meagher, Laurence; Nisbet, David; Forsythe, John S.

Description

Cells respond to their environment in complex and sometimes poorly understood ways. Protein, peptide and synthetic peptidomimetic ligands may all be used to stimulate cells via receptor signaling, using interactions that are often highly specific. Polymer substrates that present these ligands provide a promising way to control cell development, both for applications in biotechnology and for fundamental studies of cell biology. Here we review a large range of techniques that have been employed...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/23011
Source: Progress in Polymer Science (Oxford)
DOI: 10.1016/j.progpolymsci.2013.11.006

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