Skip navigation
Skip navigation

Construction of a multivalent vaccine strain of Shigella flexneri and evaluation of serotype-specific immunity

Jennison, Amy; Roberts, Fleur; Verma, Naresh

Description

Shigella flexneri causes more fatalities by shigellosis than any other Shigella species. There are 13 different serotypes of S. flexneri and their distribution varies between endemic geographical regions. The immune response against S. flexneri is serotype-specific, so current immunization strategies have required the administration of multiple vaccine strains to provide protection against multiple serotypes. In this study, we report the construction of a multivalent S. flexneri vaccine strain,...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/22753
Source: FEMS Immunology and Medical Microbiology
DOI: 10.1111/j.1574-695X.2006.00062.x

Download

File Description SizeFormat Image
01_Jennison_Construction_of_a_multivalent_2006.pdf270.95 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator