Skip navigation
Skip navigation

Structure and absolute configuration of 3-alkylpiperidine alkaloids from an Indonesian sponge of the genus Halichondria

Mudianta, Wayan; Katavic, Peter L; Lambert, Lynette K; Hayes, Patricia Y; Banwell, Martin; Munro, Murray HG; Bernhardt, Paul; Garson, Mary J


Chemical analysis of an Indonesian sponge sample has provided three new 3-alkylpiperidine alkaloids, tetradehydrohaliclonacyclamine A, its mono-N-oxide derivative, and a 2-epi isomer. The absolute structure of tetradehydrohaliclonacyclamine A has been established by X-ray crystallography from anomalous dispersion effects using Cu radiation, which determined that the absolute configuration is 2S, 3S, 7S, 9S while an HPLC study revealed that the alkaloid is enantiomerically pure.

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Tetrahedron
DOI: 10.1016/j.tet.2010.01.068


File Description SizeFormat Image
01_Mudianta_Structure_and_absolute_2010.pdf560.03 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator