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Volumetric brain differences in clinical depression in association with anxiety: a systematic review with meta-analysis

Espinoza Oyarce, Daniela Andrea; Shaw, Marnie; Alateeq, khawlah; Cherbuin, Nicolas


Background: Structural differences associated with depression have not been confirmed in brain regions apart from the hippocampus. Comorbid anxiety has been inconsistently assessed, and may explain discrepancies in previous findings. We investigated the link between depression, comorbid anxiety and brain structure. Methods: We followed Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines (PROSPERO CRD42018089286). We searched the Cochrane Library, MEDLINE,...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
Source: Journal of Psychiatry and Neuroscience
DOI: 10.1503/jpn.190156


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