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Differences in Intrinsic Tubulin Dynamic Properties Contribute to Spindle Length Control in Xenopus Species

Hirst, William; Biswas, Abin; Mahalingan, Kishore K; Reber, Simone


The function of cellular organelles relates not only to their molecular composition but also to their size. However, how the size of dynamic mesoscale structures is established and maintained remains poorly understood [1–3]. Mitotic spindle length, for example, varies several-fold among cell types and among different organisms [4]. Although most studies on spindle size control focus on changes in proteins that regulate microtubule dynamics [5–8], the contribution of the spindle’s main building...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
Source: Current Biology
DOI: 10.1016/j.cub.2020.03.067
Access Rights: Open Access


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