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Non-L-type voltage-dependant calcium channels control vascular tone of the rat basilar artery

Navarro-Gonzalez, Manuel; Grayson, Thomas; Meaney, Kate; Cribbs, Leanne; Hill, Caryl


1. Constriction of cerebral arteries is considered to depend on L-type voltage-dependent calcium channels (VDCCs); however, many previous studies have used antagonists with potential non-selective actions. Our aim was to determine the expression and function of VDCCs in the rat basilar artery. 2. The relative expression of VDCC subtypes was assessed using quantitative polymerase chain reaction and immunohistochemistry. Data were correlated with physiological studies of vascular function....[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Clinical and Experimental Pharmacology and Physiology
DOI: 10.1111/j.1440-1681.2008.05035.x


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