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A minimum reporting standard for multiple sequence alignments

Wong, Thomas; Kalyaanamoorthy, Subha; Meusemann, Karen; Yeates, David K.; Misof, Bernhard; Jermiin, Lars

Description

Multiple sequence alignments (MSAs) play a pivotal role in studies of molecular sequence data, but nobody has developed a minimum reporting standard (MRS) to quantify the completeness of MSAs. We present an MRS that relies on four simple completeness metrics. The metrics are implemented in AliStat, a program developed to support the MRS. A survey of published MSAs illustrates the benefits and unprecedented transparency offered by the MRS.

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
URI: http://hdl.handle.net/1885/223633
Source: NAR Genomics and Bioinformatics
DOI: 10.1093/nargab/lqaa024
Access Rights: Open Access

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