Developmental changes in the expression of calbindin and potassium-channel subunits Kv3.1b and Kv3.2 in mouse renshaw cells
Song, Zan-Min; Hu, Jingyao; Rudy, B; Redman, Stephen
One class of spinal interneurons, the Renshaw cells, is able to discharge at very high frequencies in adult mammals. Neuronal firing at such high frequencies requires voltage-gated potassium channels to rapidly repolarize the membrane potential after each action potential. We sought to establish the pattern of expression of calbindin and potassium channels with Kv3.1b and Kv3.2 subunits in Renshaw cells at different developmental stages of postnatal mice. The pattern of expression of calbindin...[Show more]
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|Source:||Journal of Neuroscience|
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