An apicoplast-resident folate transporter is essential for sporogony of malaria parasites
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Korbmacher, Francois; Drepper, Benjamin; Sanderson, Theo; Martin, Peer; Stach, Thomas; Maier, Alexander; Matuschewski, Kai; Matz, Joachim M.
Description
Malaria parasites are fast replicating unicellular organisms and require substantial amounts of folate for DNA synthesis. Despite the central role of this critical co-factor for parasite survival, only little is known about intraparasitic folate trafficking in Plasmodium. Here, we report on the expression, subcellular localisation and function of the parasite's folate transporter 2 (FT2) during life cycle progression in the murine malaria parasite Plasmodium berghei. Using live fluorescence...[Show more]
Collections | ANU Research Publications |
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Date published: | 2020 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/222888 |
Source: | Cellular Microbiology |
DOI: | .1111/cmi.13266 |
Access Rights: | Open Access |
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01_Korbmacher_An_apicoplast-resident_folate_2020.pdf | 3.63 MB | Adobe PDF | ![]() |
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