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Isolation of major histocompatibility complex Class I genes from the tammar wallaby (Macropus eugenii)

Deakin, Janine; Siddle, Hannah V; Baker, Michelle L; Miller, Robert D; Belov, Katherine

Description

The major histocompatibility complex (MHC) plays an essential role in the adaptive immune system of vertebrates through antigen recognition. Although MHC genes are found in all vertebrates, the MHC region is dynamic and has changed throughout vertebrate evolution, making it an important tool for comparative genomics. Marsupials occupy an important position in mammalian phylogeny, yet the MHC of few marsupials has been studied in detail. We report the isolation and analysis of expressed MHC...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/22163
Source: Immunogenetics
DOI: 10.1007/s00251-006-0107-4

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