Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice
-
Altmetric Citations
Harris, Michael A; Shekhar, Tanmay M; Coupland, Lucy; Miles, Mark A; Hawkins, Christine J
Description
Two thirds of metastatic osteosarcoma patients die within 5 years of diagnosis. Improved experimental models of osteosarcoma metastasis will facilitate the development of more effective therapies. Intravenous cancer cell injection can produce lung metastases in nude mice, but this ‘‘experimental metastasis’’ technique has been predominantly applied to a single osteosarcoma cell line (143B) and required injection of 1–2 million cells. Using two human osteosarcoma cell lines, we discovered...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2020 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/219773 |
Source: | Journal of Adolescent and Young Adult Oncology (JAYAO) |
DOI: | 10.1089/jayao.2019.0172 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Harris_Transient_NK_Cell_Depletion_2020.pdf | 582.12 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 19 May 2020/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator