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Effect of Immediate Administration of Antibiotics in Patients With Sepsis in Tertiary Care: A Systematic Review and Meta-analysis

Johnston, Amy N.B.; Park, Joon; Doi, Suhail; Sharman, Vicki; Clark, Justin; Robinson, Jemma; Crilly, Julia


Purpose: The goal of this review was to synthesize existing evidence regarding outcomes (mortality) for patients who present to the emergency department, are administered antibiotics immediately (within 1 hour) or later (41 hour), and are diagnosed with sepsis. Methods: A search of PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL, using the MeSH descriptors “sepsis,” “systemic inflammatory response syndrome,” “mortality,” “emergency,” and “antibiotics,” was...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Clinical Therapeutics
DOI: 10.1016/j.clinthera.2016.12.003


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