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Protocol and statistical analysis plan for the REstricted fluid therapy VERsus Standard trEatment in Acute Kidney Injury-REVERSE-AKI randomized controlled pilot trial

Vaara, Suvi; Ostermann, Marlies; Selander, Tuomas; Bitker, Laurent; Schneider, Antoine; Poli, Elettra; Hoste, Eric; Joannidis, Michael; Zarbock, Alexander; Van Haren, Frank; Prowle, John

Description

Background: Fluid accumulation frequently coexists with acute kidney injury (AKI) and is associated with increased risk for AKI progression and mortality. Among septic shock patients, restricted use of resuscitation fluid has been reported to reduce the risk of worsening of AKI. Restrictive fluid therapy, however, has not been studied in the setting of established AKI. Here, we present the protocol and statistical analysis plan of the REstricted fluid therapy VERsus Standard trEatment in...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
URI: http://hdl.handle.net/1885/219242
Source: Acta Anaesthesiologica Scandinavica
DOI: 10.1111/aas.13557

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