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Murine Models of Human Immune Defects

Boast, Brigette


Due to the considerable overlap between mammalian genetics and physiology, the use of lab rodents has allowed for great advancements in the understanding of human diseases and implementation of novel therapies, particularly within the cancer and immunology fields. Through the use of both forward and reverse genetics approaches, we have developed three mutant mouse strains, all with mutations in genes that are essential for correct immune development and function. The first two mutant strains...[Show more]

CollectionsRestricted Theses
Date published: 2021
Type: Thesis (PhD)
DOI: 10.25911/C6QR-5234
Embargoed until: 2022-01-14


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