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Natural Isotope Abundance in Metabolites: Techniques and Kinetic Isotope Effect Measurement in Plant, Animal, and Human Tissues

TEA, Illa; Tcherkez, Guillaume

Description

The natural isotope abundance in bulk organic matter or tissues is not a sufficient base to investigate physiological properties, biosynthetic mechanisms, and nutrition sources of biological systems. In fact, isotope effects in metabolism lead to a heterogeneous distribution of 2H, 18O, 13C, and 15N isotopes in metabolites. Therefore, compound-specific isotopic analysis (CSIA) is crucial to biological and medical applications of stable isotopes. Here, we review methods to implement CSIA for 15N...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Book chapter
URI: http://hdl.handle.net/1885/219057
DOI: 10.1016/bs.mie.2017.07.020

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