Rate matrix estimation from site frequency data
A procedure is described for estimating evolutionary rate matrices from observed site frequency data. The procedure assumes (1) that the data are obtained from a constant size population evolving according to a stationary Wright–Fisher or decoupled Moran model; (2) that the data consist of a multiple alignment of a moderate number of sequenced genomes drawn randomly from the population; and (3) that within the genome a large number of independent, neutral sites evolving with a common mutation...[Show more]
|Collections||ANU Research Publications|
|Source:||Theoretical Population Biology|
|01_Burden_Rate_matrix_estimation_from_2017.pdf||889.58 kB||Adobe PDF||Request a copy|
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