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Detection of Helicobacteraceae in Intestinal Biopsies of Children with Crohn's Disease

Kaakoush, Nadeem; Holmes, Julie; Octavia, Sophie; Man, Si Ming; Zhang, Li; Castano-Rodriguez, Natalia; Day, Andrew S.; Leach, Steven T.; Lemberg, Daniel A.; Dutt, Shoma; Stormon, Michael; O'Loughlin, Edward V.; Magoffin, Annabel; Mitchell, Hazel


BACKGROUND: Given that members of Helicobacteraceae family colonize the intestinal mucus layer, it has been hypothesized that they may play a role in Crohn's disease. This study investigated the presence of Helicobacteraceae DNA in biopsies collected from children with Crohn's disease and controls. MATERIALS AND METHODS: The presence of Helicobacteraceae DNA was investigated in intestinal biopsies collected from 179 children undergoing colonoscopy (Crohn's disease n = 77, controls n = 102)...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Helicobacter (Oxford)
DOI: 10.1111/j.1523-5378.2010.00792.x


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