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Long-term stabilization of metastatic melanoma with sodium dichloroacetate

Khan, Akbar; Andrews, Douglas; Shainhouse, Jill; Blackburn, Anneke

Description

Sodium dichloroacetate (DCA) has been studied as a metabolic cancer therapy since 2007, based on a publication from Bonnet et al demonstrating that DCA can induce apoptosis (programmed cell death) in human breast, lung and brain cancer cells. Classically, the response of cancer to a medical therapy in human research is measured by Response Evaluation Criterial for Solid Tumours definitions, which define “response” by the degree of tumour reduction, or tumour disappearance on imaging, however...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/218195
Source: World Journal of Clinical Oncology
DOI: 10.5306/wjco.v8.i4.371

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