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Functional genomics-guided discovery of a light-activated phytotoxin in the wheat pathogen Parastagonospora nodorum via pathway activation

Chooi, Yit-Heng; Zhang, Guozhi; Hu, Jinyu; Tran, Phuong; Pettitt, Amber; Maier, Alexander; Barrow, Russell; Solomon, Peter; Gonzalez, Mariano


Parastagonospora nodorum is an important pathogen of wheat. The contribution of secondary metabolites to this pathosystem is poorly understood. A biosynthetic gene cluster (SNOG_08608-08616) has been shown to be upregulated during the late stage of P.nodorum wheat leaf infection. The gene cluster shares several homologues with the Cercospora nicotianae CTB gene cluster encoding the biosynthesis of cercosporin. Activation of the gene cluster by overexpression (OE) of the transcription factor...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Environmental Microbiology
DOI: 10.1111/1462-2920.13711


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