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Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice

de Jersey, James; Snelgrove, Sarah L; Palmer, Stephanie; Teteris, Simon; Mullbacher, Arno; Miller, Jacques; Slattery, Robyn


Type 1 diabetes (T1D) is caused by the destruction of insulin-producing islet β cells. CD8 T cells are prevalent in the islets of T1D patients and are the major effectors of β cell destruction in nonobese diabetic (NOD) mice. In addition to their critic

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.0610057104


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