Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients
What is the issue? Calcineurin inhibitors (CNI, cyclosporin and tacrolimus) are an important part of treatment to suppress the immune system to prevent rejection of transplanted kidneys. However, CNI can cause high blood pressure and kidney scarring which contribute to worsening of risk factors for heart attack, stroke, and loss of the transplanted organ over time. There are conflicting data on the results of withdrawing these drugs from kidney transplant recipients; some studies suggest...[Show more]
|Collections||ANU Research Publications|
|Source:||Cochrane Database of Systematic Reviews (CDSR)|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.