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A model based on the Pennes bioheat transfer equation is valid in normal brain tissue but not brain tissue suffering focal ischaemia

Lillicrap, Thomas; Tahtalı, Murat; Neely, Andrew; Wang, Xiaofei; Bivard, Andrew; Lueck, Christian


Ischaemic stroke is a major public health issue in both developed and developing nations. Hypothermia is believed to be neuroprotective in cerebral ischaemia. Conversely, elevated brain temperature is associated with poor outcome after ischaemic stroke. Mechanisms of heat exchange in normally-perfused brain are relatively well understood, but these mechanisms have not been studied as extensively during focal cerebral ischaemia. A finite element model (FEM) of heat exchange during focal...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Australasian Physical and Engineering Sciences in Medicine
DOI: 10.1007/s13246-017-0595-6


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