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Repeated praziquantel treatment and Opisthorchis viverrini infection: a population-based cross-sectional study in northeast Thailand

Thinkhamrop, Kavin; Khuntikeo, Narong; Sithithaworn, Paiboon; Thinkhamrop, Wilaiphorn; Wangdi, Kinley; Kelly, Matthew; Suwannatrai, Apiporn T; Gray, Darren


Opisthorchis viverrini infection is highly prevalent in northeast Thailand. This liver fluke is classified as a carcinogen due to its causal links with cholangiocarcinoma (CCA) development. Although treatment with praziquantel (PZQ) effectively cures O. viverrini infection, the prevalence remains high due to the traditional consumption of raw fish. Therefore, re-infection is common in the endemic community, leading to severe hepato-biliary morbidities including the fatal CCA. In this study, we...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
Source: Infectious Diseases of Poverty
DOI: 10.1186/s40249-019-0529-5
Access Rights: Open Access


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