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Bilateral volume reduction in posterior hippocampus in psychosis of epilepsy

Allebone, James; Kanaan, Richard; Maller, Jerome; O'Brien, Terry; Mullen, Saul Alator; Cook, Mark; Adams, Sophia J.; Vogrin, Simon; Vaughan, David N.; Connelly, Alan; Kwan, Patrick

Description

Objective Psychosis of epilepsy (POE) occurs more frequently in temporal lobe epilepsy, raising the question as to whether abnormalities of the hippocampus are aetiologically important. Despite decades of investigation, it is unclear whether hippocampal volume is reduced in POE, perhaps due to small sample sizes and methodological limitations of past research. Methods In this study, we examined the volume of the total hippocampus, and the hippocampal head, body and tail, in a large cohort of...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
URI: http://hdl.handle.net/1885/216623
Source: Journal of Neurology Neurosurgery and Psychiatry
DOI: 10.1136/jnnp-2018-319396

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