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Control of tissue morphogenesis by the HOX gene Ultrabithorax

Del Carmen Diaz de la Loza, Maria; Loker, Ryan; Mann, Richard S; Thompson, Barry


Mutations in the Ultrabithorax (Ubx) gene cause homeotic transformation of the normally two-winged Drosophila into a four-winged mutant fly. Ubx encodes a HOX family transcription factor that specifies segment identity, including transformation of the second set of wings into rudimentary halteres. Ubx is known to control the expression of many genes that regulate tissue growth and patterning, but how it regulates tissue morphogenesis to reshape the wing into a haltere is still unclear. Here, we...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
Source: Development
DOI: 10.1242/dev.184564
Access Rights: Open Access


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