Environmental Risk Factors for Multiple Sclerosis: A Review with a Focus on Molecular Mechanisms
Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system commonly affecting young adults. Pathologically, there are patches of inflammation (plaques) with demyelination of axons and oligodendrocyte loss. There is a global latitude gradient in MS prevalence, and incidence of MS is increasing (particularly in females). These changes suggest a major role for environmental factors in causation of disease. We have reviewed the evidence and potential mechanisms of action...[Show more]
|Collections||ANU Research Publications|
|Source:||International Journal of Molecular Sciences|
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