Regulation of MicroRNA by Antagomirs: A New Class of Pharmacological Antagonists for the Specific Regulation of Gene Function?
The discovery of small "noncoding" or "nonmessenger" RNA molecules that are repressors of translation (microRNAs) has provided the opportunity to specifically suppress a gene or clusters of genes. Moreover, the recent employment of synthetic analogs of these small RNA molecules termed "antagomirs" has shown that microRNAs of interest can be specifically targeted. Understanding the role of microRNAs in fundamental processes associated with complex diseases such as asthma, chronic obstructive...[Show more]
|Collections||ANU Research Publications|
|Source:||American Journal of Respiratory Cell and Molecular Biology|
|01_Mattes_Regulation_of_MicroRNA_by_2007.pdf||1.07 MB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.