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Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort

Hassiotis, Angela; Brown, Emma; Harris, James; Helm, David; Munir, Kerim; Salvador-Carulla, Luis; Bertelli, Marco O.; Baghdadli, Amaria; Wieland, Jannelien; Novell-Alsina, Ramon; Cid, Jordi

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BACKGROUND: To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS: We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age...[Show more]

dc.contributor.authorHassiotis, Angela
dc.contributor.authorBrown, Emma
dc.contributor.authorHarris, James
dc.contributor.authorHelm, David
dc.contributor.authorMunir, Kerim
dc.contributor.authorSalvador-Carulla, Luis
dc.contributor.authorBertelli, Marco O.
dc.contributor.authorBaghdadli, Amaria
dc.contributor.authorWieland, Jannelien
dc.contributor.authorNovell-Alsina, Ramon
dc.contributor.authorCid, Jordi
dc.date.accessioned2020-11-05T00:04:48Z
dc.date.available2020-11-05T00:04:48Z
dc.identifier.issn1471-244X
dc.identifier.urihttp://hdl.handle.net/1885/213690
dc.description.abstractBACKGROUND: To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS: We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. RESULTS: Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104-0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. CONCLUSIONS: The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group.
dc.description.sponsorshipThe BIF Consensus Group was sponsored by the Institut d’Assistència Sanitària, the Government of Catalunya (RN-A, LV, JC), the NCD-Lifespan (TW98045) and Global RD0C (TW009680) Fogarty/NIMH grants at the Boston Children’s Hospital, Harvard Medical School (K Munir), and the Mental Health Policy Unit, the Centre for Disability Research and Policy Faculty of Health Sciences, University of Sydney (L Salvador-Carulla, E Emerson).
dc.format.mimetypeapplication/pdf
dc.language.isoen_AU
dc.publisherBioMed Central
dc.rights© The Author(s).
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceBMC Psychiatry
dc.titleAssociation of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume19
dc.date.issued2019
local.identifier.absfor111714 - Mental Health
local.identifier.ariespublicationu4102339xPUB467
local.publisher.urlhttps://doaj.org/toc/1471-244X
local.type.statusPublished Version
local.contributor.affiliationHassiotis , Angela , Division of Psychiatry, University College London
local.contributor.affiliationBrown , Emma , Division of Psychiatry, University College London
local.contributor.affiliationHarris , James , Department of Psychiatry and Behavioral Sciences, Bloomberg Children's Center
local.contributor.affiliationHelm, David , Division of Developmental Medicine, Boston Children's Hospital
local.contributor.affiliationMunir, Kerim, Boston Children's Hospital
local.contributor.affiliationSalvador-Carulla, Luis, College of Health and Medicine, ANU
local.contributor.affiliationBertelli, Marco O., Research and Clinical Centre (CREA), San Sebastiano Foundation
local.contributor.affiliationBaghdadli, Amaria, Montpellier Hospital University
local.contributor.affiliationWieland, Jannelien, Kristal Centre for Psychiatry and Intellectual Disability
local.contributor.affiliationNovell-Alsina, Ramon, Mental Health and Intellectual Disability Specialized Service
local.contributor.affiliationCid, Jordi, Mental Health and Intellectual Disability Specialized Service
local.bibliographicCitation.issue387
local.bibliographicCitation.startpage1
local.bibliographicCitation.lastpage9
local.identifier.doi10.1186/s12888-019-2376-0
local.identifier.absseo920410 - Mental Health
dc.date.updated2020-07-06T08:24:06Z
dcterms.accessRightsOpen Access
dc.provenance© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.rights.licenseCreative Commons Attribution 4.0 International License
CollectionsANU Research Publications

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