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Protein NMR Using Paramagnetic Ions

Otting, Gottfried


Paramagnetic metal ions offer outstanding opportunities for protein studies by nuclear magnetic resonance (NMR) spectroscopy. The paramagnetic effects manifested in the NMR spectra provide powerful restraints for the determination of the three-dimensional structure of proteins, open new possibilities for the analysis of protein-protein and protein-ligand interactions, and offer widely applicable tools for sensitivity enhancement of NMR experiments, resonance assignments, and studies of...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Annual Review of Biophysics
DOI: 10.1146/annurev.biophys.093008.131321


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