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Capsid gene divergence in rabbit hemorrhagic disease virus

Kinnear, Mark; Linde, Celeste


The emergence and rapid global spread of rabbit hemorrhagic disease virus (RHDV) remains enigmatic despite two decades of study, largely due to the difficulties associated with modelling substitution processes of the RNA genome for phylogenetic inference. We used maximum-likelihood and Bayesian methods to investigate rates of molecular evolution in the capsid gene, finding evidence of positive selection and of variable substitution rates between nucleotide sites and between lineages. The...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Journal of General Virology
DOI: 10.1099/vir.0.014076-0


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