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An isolated complex v inefficiency and dysregulated mitochondrial function in immortalized lymphocytes from ME/CFS patients

Missailidis, Daniel; Annesley, Sarah; Allan, Claire Y.; Sanislav, Oana; Lidbury, Brett; Lewis, Donald P.; Fisher, Paul

Description

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an enigmatic condition characterized by exacerbation of symptoms after exertion (post-exertional malaise or “PEM”), and by fatigue whose severity and associated requirement for rest are excessive and disproportionate to the fatigue-inducing activity. There is no definitive molecular marker or known underlying pathological mechanism for the condition. Increasing evidence for aberrant energy metabolism suggests a role...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
URI: http://hdl.handle.net/1885/209347
Source: International Journal of Molecular Sciences
DOI: 10.3390/ijms21031074
Access Rights: Open Access

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